Eddie Gato Wolfe is a young, impetuous member of the Wolfe clan of Texas gun-runners and bootleggers that goes back generations. Increasingly unfulfilled by his minor role in family operations and eager to set out on his own, Eddie crosses the border to work security for a major Mexican drug cartel led by the ruthless La Navaja. At a party, Eddie falls for a beautiful woman named Miranda, whom he learns too late is the girlfriend of El Segundo, La Navaja's only living brother. When El Segundo finds Eddie and Miranda together, Eddie is given no choice but to kill him, forcing the two lovers to flee the cartel in hopes of crossing the border and reuniting with the Wolfe family. But La Navaja's reach is far and his lust for revenge insatiable. He sends a horde of operatives and the notorious bounty hunter El Martillo after the pair. If La Navaja's men don't kill Eddie and Miranda, the brutal Mexican desert just may. Their only hope: help from the family that Eddie abandoned.